The genetics of natalizumab hypersensitivity
One learns to itch where one can scratch
Citation Manager Formats
Make Comment
See Comments

Article Information
- First Published December 11, 2014.
Author Disclosures
- Olaf Stüve, MD, PhD and
- Bernhard Hemmer, MD
- Olaf Stüve, MD, PhD and
NONE
NONE
NONE
JAMA Neurology Therapeutic Advances in Neurological Disorders Clinical and Experimental Immunology MS Journal
NONE
NONE
NONE
NONE
NONE
NONE
NONE
Teva Pharmaceuticals Opexa Therapeutics
Merit Review Grant Department of Veterans Affairs
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Bernhard Hemmer, MD
Advisory board member for trials conducted by Bayer, BiogenIdec, Roche, Novartis, MerckSerono, Chugai, GSK, Genentech.
NONE
Sponsoring was received from Bayer, BiogenIdec, Roche, Novartis, MerckSerono for travelling and talks
NONE
(1) Anti-KIR4.1 antibody testing in MS (2) Genetic factors influencing the development of NABs
NONE
NONE
Gerson Lehrman Group
NONE
NONE
NONE
Research support from Bayer, BiogenIdec, Roche, Novartis, MerckSerono, Metanomics, Chugai Pharmaceuticals and Protagen.
Deutsche Forschungsgemeinschaft, Bundesministerium f?r Bildung und Forschung, European Community.
NONE
Competence Network for Multiple Sclerosis Synergy Excellence Cluster German Research Foundation Bundesministerium f?r Bildung und Forschung
NONE
NONE
NONE
NONE
NONE
NONE
- From the Department of Neurology and Neurotherapeutics (O.S.), University of Texas Southwestern Medical Center, Dallas, TX; Neurology Section (O.S.), VA North Texas Health Care System, Medical Service, Dallas, TX; Department of Neurology (O.S., B.H.), Klinikum rechts der Isar, Technische Universität München, Germany; and Munich Cluster for Systems Neurology (SyNergy) (B.H.), Munich, Germany.
- Correspondence to Dr. Stüve: olaf.stuve{at}utsouthwestern.edu
Article usage
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Hastening the Diagnosis of Amyotrophic Lateral Sclerosis
Dr. Brian Callaghan and Dr. Kellen Quigg
► Watch
Related Articles
- No related articles found.
Topics Discussed
Alert Me
Recommended articles
-
Article
Natalizumab-related anaphylactoid reactions in MS patients are associated with HLA class II allelesBelén de la Hera, Elena Urcelay, David Brassat et al.Neurology - Neuroimmunology Neuroinflammation, December 11, 2014 -
Article
Preclinical development and first-in-human study of ATX-MS-1467 for immunotherapy of MSHeather B. Streeter, Rachel Rigden, Keith F. Martin et al.Neurology - Neuroimmunology Neuroinflammation, March 12, 2015 -
Articles
GLANCEResults of a phase 2, randomized, double-blind, placebo-controlled studyA. D. Goodman, H. Rossman, A. Bar-Or et al.Neurology, March 02, 2009 -
Article
Genetic determinants of the humoral immune response in MSChristiane Gasperi, Till F.M. Andlauer, Ana Keating et al.Neurology: Neuroimmunology & Neuroinflammation, July 16, 2020