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August 2015; 2 (4) Clinical/Scientific NotesOpen Access

Sleep disorder, chorea, and dementia associated with IgLON5 antibodies

Mateus M. Simabukuro, Lidia Sabater, Tarso Adoni, Rubens Gisbert Cury, Mônica Santoro Haddad, Camila Hobi Moreira, Luana Oliveira, Mateus Boaventura, Rosana Cardoso Alves, Leticia Azevedo Soster, Ricardo Nitrini, Carles Gaig, Joan Santamaria, Josep Dalmau, Francesc Graus
First published July 23, 2015, DOI: https://doi.org/10.1212/NXI.0000000000000136
Mateus M. Simabukuro
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Lidia Sabater
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Tarso Adoni
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Rubens Gisbert Cury
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Mônica Santoro Haddad
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Camila Hobi Moreira
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Luana Oliveira
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Mateus Boaventura
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Rosana Cardoso Alves
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Leticia Azevedo Soster
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Ricardo Nitrini
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Carles Gaig
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Joan Santamaria
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Josep Dalmau
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Francesc Graus
From the Neurology Division (M.M.S., T.A., R.G.C., M.S.H., C.H.M., L.O., M.B., R.C.A., L.A.S., R.N.), Hospital das Clínicas, São Paulo University (HC/FMUSP), Brazil; August Pi I Sunyer Biomedical Research Institute (IDIBAPS) (L.S., J.D., F.G.), Barcelona, Spain; Hospital Clínic (C.G., J.S., F.G.), University of Barcelona, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Catalan Institution for Research and Advanced Studies (ICREA) (J.D.), Barcelona, Spain.
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Full PDF
Citation
Sleep disorder, chorea, and dementia associated with IgLON5 antibodies
Mateus M. Simabukuro, Lidia Sabater, Tarso Adoni, Rubens Gisbert Cury, Mônica Santoro Haddad, Camila Hobi Moreira, Luana Oliveira, Mateus Boaventura, Rosana Cardoso Alves, Leticia Azevedo Soster, Ricardo Nitrini, Carles Gaig, Joan Santamaria, Josep Dalmau, Francesc Graus
Neurol Neuroimmunol Neuroinflamm Aug 2015, 2 (4) e136; DOI: 10.1212/NXI.0000000000000136

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