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October 2015; 2 (5) Clinical/Scientific NotesOpen Access

Plasticity-related gene 5: A novel surface autoantigen in paraneoplastic cerebellar degeneration

Marleen H. van Coevorden-Hameete, Esther de Graaff, Maarten J. Titulaer, Esther Hulsenboom, Lidia Sabater, Casper C. Hoogenraad, Peter A. Sillevis Smitt
First published September 24, 2015, DOI: https://doi.org/10.1212/NXI.0000000000000156
Marleen H. van Coevorden-Hameete
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Esther de Graaff
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Maarten J. Titulaer
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Esther Hulsenboom
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Lidia Sabater
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Casper C. Hoogenraad
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Peter A. Sillevis Smitt
From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
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Full PDF
Citation
Plasticity-related gene 5: A novel surface autoantigen in paraneoplastic cerebellar degeneration
Marleen H. van Coevorden-Hameete, Esther de Graaff, Maarten J. Titulaer, Esther Hulsenboom, Lidia Sabater, Casper C. Hoogenraad, Peter A. Sillevis Smitt
Neurol Neuroimmunol Neuroinflamm Oct 2015, 2 (5) e156; DOI: 10.1212/NXI.0000000000000156

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Article Information

vol. 2 no. 5 e156
DOI: 
https://doi.org/10.1212/NXI.0000000000000156
PubMed: 
26445730

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Online ISSN: 
2332-7812
History: 
  • Received June 23, 2015
  • Accepted in final form August 5, 2015
  • First Published September 24, 2015.

Copyright & Usage: 
© 2015 American Academy of Neurology This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially.

Author Disclosures

    1. Marleen H. van Coevorden-Hameete, MD,
    2. Esther de Graaff, PhD,
    3. Maarten J. Titulaer, MD, PhD,
    4. Esther Hulsenboom, BSc,
    5. Lidia Sabater, BSc,
    6. Casper C. Hoogenraad, PhD and
    7. Peter A. Sillevis Smitt, MD, PhD
  1. Marleen H. van Coevorden-Hameete, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Esther de Graaff, PhD,
  4. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. (1)co-investor: the detection anti-DNER antibodies

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Maarten J. Titulaer, MD, PhD,
  6. Scientific Advisory Boards:
    1. (1) Serve on the scientific advisory board of MedImmune LLC.

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. (1) Sun Pharma, travel grant for lecturing in India

    Editorial Boards:
    1. (1) Neurology: Neuroimmunology & Neuroinflammation, since June 2014

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. (1) supported by the Netherlands Organisation for Scientific Research (NWO, Veni incentive)

    Research Support, Academic Entities:
    1. (1) Currently supported by an ErasmusMC fellowship

    Research Support, Foundations and Societies:
    1. (1) supported by the Dutch Epilepsy Foundations, projectnumber 14-19.

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Esther Hulsenboom, BSc,
  8. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Lidia Sabater, BSc,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Casper C. Hoogenraad, PhD and
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Peter A. Sillevis Smitt, MD, PhD
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. Peter Sillevis Smitt is co-inventor of a pending patent on the detection anti-DNER

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. Peter Sillevis Smitt received a research grant from Euroimmun.

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Biology (M.H.v.C.-H., E.d.G., C.C.H.), div Cell Biology, Utrecht University, Utrecht, the Netherlands; Department of Neurology (M.H.v.C.-H, M.J.T., E.H., P.A.S.S.), Erasmus Medical Center, Rotterdam, the Netherlands; and Service of Neurology Hospital Clinic (L.S.), Institut d'Investigació Biomèdica August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
  1. Correspondence to Dr. Smitt: p.sillevissmitt{at}erasmusmc.nl
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