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April 2016; 3 (2) Clinical/Scientific NotesOpen Access

Failure of alemtuzumab as a rescue in a NMOSD patient treated with rituximab

Markus C. Kowarik, Muna Hoshi, Bernhard Hemmer, Achim Berthele
First published February 10, 2016, DOI: https://doi.org/10.1212/NXI.0000000000000208
Markus C. Kowarik
From Klinikum rechts der Isar der Technischen Universität München (M.C.K., M.H., B.H., A.B.); and Munich Cluster for Systems Neurology (SyNergy) (B.H.), Germany.
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Muna Hoshi
From Klinikum rechts der Isar der Technischen Universität München (M.C.K., M.H., B.H., A.B.); and Munich Cluster for Systems Neurology (SyNergy) (B.H.), Germany.
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Bernhard Hemmer
From Klinikum rechts der Isar der Technischen Universität München (M.C.K., M.H., B.H., A.B.); and Munich Cluster for Systems Neurology (SyNergy) (B.H.), Germany.
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Achim Berthele
From Klinikum rechts der Isar der Technischen Universität München (M.C.K., M.H., B.H., A.B.); and Munich Cluster for Systems Neurology (SyNergy) (B.H.), Germany.
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Citation
Failure of alemtuzumab as a rescue in a NMOSD patient treated with rituximab
Markus C. Kowarik, Muna Hoshi, Bernhard Hemmer, Achim Berthele
Neurol Neuroimmunol Neuroinflamm Apr 2016, 3 (2) e208; DOI: 10.1212/NXI.0000000000000208

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    Figure Clinical course, treatment, and lymphocyte populations

    (A) Clinical course and treatment between March 2009 and January 2014. The period of alemtuzumab treatment is shaded. (B) CD4+ and CD8+ T cells in the peripheral blood during and after alemtuzumab treatment between January 2010 and April 2012. Flat lines indicate the lower limit of normal. (C) CD19+ B cells in peripheral blood.

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