Article Figures & Data
Figures
- Figure. Paraneoplastic neuromyelitis optica spectrum disorder associated with anti-aquaporin-4 (AQP4) immunoreactivity in an oncocytic thyroid carcinoma
Micrographs show immunohistochemistry performed on formalin-fixed paraffin-embedded sections of the follicular carcinoma, thin-sectioned and stained for AQP4 and toluidine blue (A, C, D). (A) A sharp border between the neoplastic thyroid tissue (left) and normal thyroid tissue parenchyma (right); (B) (insert) shows negative control. (C) Multifocal high-level expression of AQP4 in the neoplastic thyroid cells, which is distinctly different from the normal thyroid tissue. (D) Magnified view of B shows AQP4 immunoreactivity predominately in the cell membrane (arrowheads). Scale bars = 200 μm (A, B), 100 μm (C), 20 μm (D).
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