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November 2018; 5 (6) Clinical/Scientific NotesOpen Access

Posttransplant autoimmune encephalitis

Devon A. Cohen, A. Sebastian Lopez-Chiriboga, Sean J. Pittock, Avi Gadoth, Anastasia Zekeridou, Barry A. Boilson, William J. Hogan, John J. Poterucha, Katelynn M. Wilton, Yi Lin, Eoin P. Flanagan
First published August 20, 2018, DOI: https://doi.org/10.1212/NXI.0000000000000497
Devon A. Cohen
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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A. Sebastian Lopez-Chiriboga
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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Sean J. Pittock
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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Avi Gadoth
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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Anastasia Zekeridou
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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Barry A. Boilson
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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William J. Hogan
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MB, BCh
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John J. Poterucha
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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Katelynn M. Wilton
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
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Yi Lin
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD, PhD
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Eoin P. Flanagan
From the Department of Neurology (D.A.C., A.S.L-C., S.J.P., A.G., A.Z., E.P.F.), Department of Laboratory Medicine and Pathology (S.J.P., E.P.F.), Department of Medicine, Divisions of Cardiology (B.A.B.), Department of Hematology (W.J.H., Y.L.), Department of Gastroenterology (J.J.P.), and Mayo Medical School (K.M.W.), Mayo Clinic, Rochester, MN.
MD
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Full PDF
Citation
Posttransplant autoimmune encephalitis
Devon A. Cohen, A. Sebastian Lopez-Chiriboga, Sean J. Pittock, Avi Gadoth, Anastasia Zekeridou, Barry A. Boilson, William J. Hogan, John J. Poterucha, Katelynn M. Wilton, Yi Lin, Eoin P. Flanagan
Neurol Neuroimmunol Neuroinflamm Nov 2018, 5 (6) e497; DOI: 10.1212/NXI.0000000000000497

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    Figure MRI of posttransplant autoimmune encephalitis

    (A) Right mesial temporal T2-hyperintensity (arrow) on coronal Fluid-attenuated inversion recovery (FLAIR) in a patient with posttransplant anti-NMDA receptor encephalitis. (B) Bilateral (right more than left) mesial temporal T2-hyperintensity (arrows) in a patient with posttransplant anti-AMPA receptor encephalitis. (C) Concurrent midbrain enhancement (arrow) and bilateral optic nerve enhancement (arrowheads) in patient with posttransplant myelin oligodendrocyte glycoprotein antibody disease.

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