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November 2019; 6 (6) EditorialOpen Access

Untangling normal aging from disease-related brain atrophy in MS

Tim Sinnecker, Jens Wuerfel
First published September 25, 2019, DOI: https://doi.org/10.1212/NXI.0000000000000617
Tim Sinnecker
From the Departments of Medicine (T.S.), Neurologic Clinic and Policlinic, University Hospital Basel and University of Basel; qbig (T.S., J.W.), Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel; Medical Image Analysis Center Basel AG (T.S., J.W.); and Translational Imaging in Neurology [ThINK] Basel (T.S.), Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel, Switzerland.
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Jens Wuerfel
From the Departments of Medicine (T.S.), Neurologic Clinic and Policlinic, University Hospital Basel and University of Basel; qbig (T.S., J.W.), Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel; Medical Image Analysis Center Basel AG (T.S., J.W.); and Translational Imaging in Neurology [ThINK] Basel (T.S.), Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel, Switzerland.
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Citation
Untangling normal aging from disease-related brain atrophy in MS
Tim Sinnecker, Jens Wuerfel
Neurol Neuroimmunol Neuroinflamm Nov 2019, 6 (6) e617; DOI: 10.1212/NXI.0000000000000617

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Article Information

vol. 6 no. 6 e617
DOI: 
https://doi.org/10.1212/NXI.0000000000000617

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Online ISSN: 
2332-7812
History: 
  • Received July 31, 2019
  • Accepted in final form August 19, 2019
  • First Published September 25, 2019.

Copyright & Usage: 
Copyright © 2019 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

Author Disclosures

    1. Tim Sinnecker, MD and
    2. Jens Wuerfel, MD
  1. Tim Sinnecker, MD and
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. (1) Commercial entity, travel support from Actelion. (2) Commercial entity, travel support from Roche. (3) Commercial entity, speaker fees from Biogen.

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. (1) non-profit entity, Medical Image Analysis Center Basel, part-time employee, research associate, three years

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Jens Wuerfel, MD
  4. Scientific Advisory Boards:
    1. 2017: Genzyme, Roche advisory board 2018: Roche, Novartis advisory board 2019: Roche advisory board

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. 2012-2016: Bayer, Biogen, Novartis speaker honoraria

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. CEO, MIAC AG, Switzerland (non-profit organisation)

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. German ministry of education and research (BMBF/KKNMS), subinvestigator, 2013-2016; and the German ministry of economy (BMWi), EXIST program and EU (Horizon2020)

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Departments of Medicine (T.S.), Neurologic Clinic and Policlinic, University Hospital Basel and University of Basel; qbig (T.S., J.W.), Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel; Medical Image Analysis Center Basel AG (T.S., J.W.); and Translational Imaging in Neurology [ThINK] Basel (T.S.), Department of Medicine and Biomedical Engineering, University Hospital Basel and University of Basel, Switzerland.
  1. Correspondence
    Dr. Sinnecker Tim.Sinnecker{at}usb.ch
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