Article Figures & Data
Figures
- Figure 1 Measurement of serum immunoglobulin (IgG, IgA, and IgM) levels in alemtuzumab-treated patients
Serum IgG (A), IgM (B), and IgA (C) levels (in g/L) were analyzed before the first alemtuzumab course and at 12 and 24 months. Stars represent levels of significance (**p < 0.01; ***p < 0.001).
- Figure 2 Measurement of CSF immunoglobulin (IgG, IgA, and IgM) levels in alemtuzumab-treated patients
CSF IgG (A), IgM (B), and IgA (C) concentrations (in mg/L) were analyzed before the first alemtuzumab course and at 12 and 24 months. In addition, quantitative fraction of intrathecal IgG synthesis over time is shown (D). Stars represent levels of significance (**p < 0.01; ***p < 0.001). OCB = oligoclonal band.
- Figure 3 Serum immunoglobulin levels of patients with third alemtuzumab course compared with controls and treatment-naive patients with MS
Samples were collected 36 months after initiation of therapy; serum IgG (A), IgM (B), and IgA (C) levels (in g/L) were measured. Controls had received 2 courses of alemtuzumab treatment and were matched to third-course patients. Samples taken from third-course patients and treatment-naive patients with MS were analyzed after thawing. Stars represent levels of significance (**p < 0.01 vs control).
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