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July 2020; 7 (4) Clinical/Scientific NotesOpen Access

Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy after alemtuzumab therapy in kidney transplant recipients

View ORCID ProfileMarieke van der Zwan, Dennis A. Hesselink, View ORCID ProfileEsther Brusse, Pieter A. van Doorn, View ORCID ProfileMartijn W.F. van den Hoogen, View ORCID ProfileAnnelies E. de Weerd, Bart C. Jacobs
First published April 16, 2020, DOI: https://doi.org/10.1212/NXI.0000000000000721
Marieke van der Zwan
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Dennis A. Hesselink
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Esther Brusse
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Pieter A. van Doorn
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Martijn W.F. van den Hoogen
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Annelies E. de Weerd
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Bart C. Jacobs
From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
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Full PDF
Citation
Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy after alemtuzumab therapy in kidney transplant recipients
Marieke van der Zwan, Dennis A. Hesselink, Esther Brusse, Pieter A. van Doorn, Martijn W.F. van den Hoogen, Annelies E. de Weerd, Bart C. Jacobs
Neurol Neuroimmunol Neuroinflamm Jul 2020, 7 (4) e721; DOI: 10.1212/NXI.0000000000000721

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This article has a correction. Please see:

  • Errata - November 01, 2020
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Article Information

vol. 7 no. 4 e721
DOI: 
https://doi.org/10.1212/NXI.0000000000000721
PubMed: 
32299841

Published By: 
Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology
Online ISSN: 
2332-7812
History: 
  • Received November 25, 2019
  • Accepted in final form March 13, 2020
  • First Published April 16, 2020.

Copyright & Usage: 
Copyright © 2020 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of the American Academy of Neurology. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND), which permits downloading and sharing the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.

Author Disclosures

    1. Marieke van der Zwan, MD,
    2. Dennis A. Hesselink, MD, PhD,
    3. Esther Brusse, MD, PhD,
    4. Pieter A. van Doorn, MD, PhD,
    5. Martijn W.F. van den Hoogen, MD, PhD,
    6. Annelies E. de Weerd, MD and
    7. Bart C. Jacobs, MD, PhD
  1. Marieke van der Zwan, MD,
  2. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. Netherlands journal of medicine, associate editor, from 2017 onwards

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  3. Dennis A. Hesselink, MD, PhD,
  4. Scientific Advisory Boards:
    1. Scientific advisory board for Chiesi Pharma SpA.

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Speaker honorariums from Astellas Pharma and Chiesi Pharma SpA.

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. Astellas Pharma.

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  5. Esther Brusse, MD, PhD,
  6. Scientific Advisory Boards:
    1. (1) I serves as an (unpaid)member of the Medical Advisory Board of the Dutch ADCA patient foundation (non- profit entity).

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. (1) Dutch ADCA patient foundation.

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  7. Pieter A. van Doorn, MD, PhD,
  8. Scientific Advisory Boards:
    1. Advisory committee (GBS). Annexion. 2019 Advisory committee (GBS). Hansa Pharmaceuticals 2019 Advisory committee (CIDP). Argenx 2019 Advisory committee (CIDP). Octapharma. 2017, 2019

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. CSL honorarium symposium talk (2019)

    Editorial Boards:
    1. Journal of Neurological Sciences, Journal of Neuromuscular Diseases: member of editorial board

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. Research support investigator initiated trials: Sanguin Blood supply (SID-GBS study) Takeda (DRIP study)

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  9. Martijn W.F. van den Hoogen, MD, PhD,
  10. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. 1. Astellas Pharma, funding for travel to conference 2. Amgen, funding for travel to conference 3. Sanofi, speaker honoraria 4. Vifor, speaker honoraria 5. Genzyme, funding for travel to conference 6. MSD, speaker honoraria

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. 1. Novartis 2. Shire

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  11. Annelies E. de Weerd, MD and
  12. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for Travel or Speaker Honoraria:
    1. NONE

    Editorial Boards:
    1. NONE

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. NONE

    Research Support, Government Entities:
    1. NONE

    Research Support, Academic Entities:
    1. NONE

    Research Support, Foundations and Societies:
    1. NONE

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  13. Bart C. Jacobs, MD, PhD
  14. Scientific Advisory Boards:
    1. NONE

    Gifts:
    1. NONE

    Funding for travel or speaker honoraria:
    1. Funding for travel from Baxter International Inc for a scientific meeting.

    Editorial Boards:
    1. Journal of the Peripheral Nervous System, member of the editorial board, 2011 - 2018.

    Patents:
    1. NONE

    Publishing Royalties:
    1. NONE

    Employment, Commercial Entity:
    1. NONE

    Consultancies:
    1. NONE

    Speakers' Bureaus:
    1. NONE

    Other Activities:
    1. NONE

    Clinical Procedures or Imaging Studies:
    1. NONE

    Research Support, Commercial Entities:
    1. (1) unrestricted research funding, eSPIN Award 2013, Grifols (2) unrestricted research funding, 2014, CSL-Behring (3) Interlaken Leadership Award 2014, CSL-Behring (4) unrestricted research funding, 2014, Baxalta (5) unrestricted research funding, 2017/2019, Annexon (6) unrestricted research funding, 2019, Hansa Medical AB

    Research Support, Government Entities:
    1. Netherlands Organization for Health Research and Development

    Research Support, Academic Entities:
    1. (1) ZikaPLAN, Horizon 2020 (EU)

    Research Support, Foundations and Societies:
    1. (1) Erasmus MC grant, PI, 2007-2011 (2) Prinses Beatrix Prinses Beatrix Spierfonds (W.OR07- 27), PI, 2007-2009 (3) Prinses Beatrix Prinses Beatrix Spierfonds (W.OR07- 28), PI, 2007-2011 (4) GBS-CIDP Foundation International, PI, 2009 (5) GBS-CIDP Foundation International, PI, 2011 (6) Prinses Beatrix Fonds (W.OR11-27), PI, 2011 (7) Prinses Beatrix Spierfonds (W.OR12-04), PI, 2012 (8) Prinses Beatrix Spierfonds (W.OR14-04), Co-PI, 2014 (9) Prinses Beatrix Spierfonds (W.OR16-18), PI, 2016 (10) Prinses Beatrix Spierfonds (prof chair), PI, 2016-19 (11) Prinses Beatrix Spierfonds (W.OR19-24), PI, 2019

    Stock/Stock Options/Board of Directors Compensation:
    1. NONE

    License Fee Payments, Technology or Inventions:
    1. NONE

    Royalty Payments, Technology or Inventions:
    1. NONE

    Stock/Stock Options, Research Sponsor:
    1. NONE

    Stock/Stock Options, Medical Equipment & Materials:
    1. NONE

    Legal Proceedings:
    1. NONE

  1. From the Department of Internal Medicine (M.Z., D.A.H., M.W.F.H., A.E.W.), Division of Nephrology and Transplantation; Rotterdam Transplant Group (M.Z., D.A.H., M.W.F.H., A.E.W.); Department of Neurology (E.B., P.A.D., B.C.J.); and Immunology (E.B., P.A.D., B.C.J.), Erasmus MC, University Medical Center Rotterdam, the Netherlands.
  1. Correspondence
    Dr. van der Zwan m.vanderzwan{at}erasmusmc.nl
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  • Guillain-Barré syndrome and chronic inflammatory demyelinating polyradiculoneuropathy after alemtuzumab therapy in kidney transplant recipients

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