Article Figures & Data
Figures
- Figure 1 AQP4-IgG (binding and complement-mediated cell killing) titers of specimens drawn at different time points (remission, preattack, and attack) in individual patients (original titer values shown in transformed scale)
(A.a) AQP4-IgG titers grouped into preattack, attack, and remission categories. (B.a) AQP4-IgG titers categorized according to baseline immunotherapy*. (C.a) AQP4-IgG titers categorized by attack severity type**. (A.b) AQP4 complement-mediated cell killing titers grouped into preattack, attack, and remission categories. (B.b) AQP4 complement-mediated cell killing titers categorized according to baseline immunotherapy*. (C.b) AQP4 complement-mediated cell killing titers categorized grouped into attack severity type**. *Immunotherapy included azathioprine, mycophenolate mofetil, cyclophosphamide, and rituximab. **Definition in the supplement. AQP4 = aquaporin-4; IgG = immunoglobulin G; IST = immunosuppressive therapy.
- Figure 2 Kaplan-Meier estimates of time to develop EDSS score ≥ 6
Years from the first aquaporin-4–immunoglobulin G complement-mediated cell killing titers to develop EDSS score ≥6. All Martinique patients, any patients with unknown status for each outcome, and any patients with missing complement values were excluded from the corresponding analysis. EDSS = Expanded Disability Status Scale.
- Figure 3 Correlation between M23-AQP4 end titer and M23-AQP4 complement-mediated cell killing titers
AQP4 = aquaporin-4; IgG = immunoglobulin G.
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