Placental transfer of NMDAR antibodies causes reversible alterations in mice
Citation Manager Formats
Make Comment
See Comments

Article Information
- Received July 13, 2020
- Accepted in final form August 26, 2020
- First Published November 10, 2020.
Author Disclosures
- Anna García-Serra, MSc,
- Marija Radosevic, PhD,
- Anika Pupak, MSc,
- Veronica Brito, PhD,
- José Ríos, MSc,
- Esther Aguilar, BS,
- Estibaliz Maudes, MSc,
- Helena Ariño, MD, PhD,
- Marianna Spatola, MD, PhD,
- Francesco Mannara, PhD,
- Marta Pedreño, PhD,
- Bastien Joubert, MD, PhD,
- Silvia Ginés, PhD,
- Jesús Planagumà, PhD* and
- Josep Dalmau, MD, PhD*
- Anna García-Serra, MSc,
None
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
FI-AGAUR grant program by the Generalitat de Catalunya, 2019FI_B1 00212, PhD student, 1 year
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
- Marija Radosevic, PhD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Anika Pupak, MSc,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
(1) Generalitat de Catalunya, FI-AGAUR grant program (2018FI_B_00487), PhD Student (2018-2021)
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Veronica Brito, PhD,
NONE
NONE
NONE
Frontiers of Cellular Neuroscience journal, Guess associate editor, 2019- present, No compensation
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- José Ríos, MSc,
None
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
Centres de recerca de Catalunya (CERCA) program, La Generalitat de Catalunya
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
- Esther Aguilar, BS,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Estibaliz Maudes, MSc,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
(1) Basque Government Doctoral Fellowship Programme, PRE_2019_1_0255.
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Helena Ariño, MD, PhD,
None
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
- Marianna Spatola, MD, PhD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
American Academy of Neurology Neuroscience Research Scholarship
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Francesco Mannara, PhD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Marta Pedreño, PhD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
- Bastien Joubert, MD, PhD,
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
Academy of neurology research fellowship grant, 2018 Institut Servier (Paris, France) research grant 2019
NONE
NONE
NONE
NONE
NONE
NONE
- Silvia Ginés, PhD,
None
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
- Jesús Planagumà, PhD* and
None
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
NONE
Generalitat de Catalunya/(PERIS),(SLT002-16-00346),Post-Doc, 3 year.
NONE
None
NONE
NONE
NONE
NONE
NONE
NONE
- Josep Dalmau, MD, PhD*
NONE
NONE
NONE
Neurology, Neuroimmunology and Neuroinflammation Neurology
Patent for Ma2 autoantibody test: US 6,387,639; Issued May 14th, 2002. Patent for NMDA receptor autoantibody test: US 7,972,796 B2 July 5, 2011; European 2057466. Patent for GABAb receptor autoantibody test: US 8,685,656; European 2483417; Patents filed for GABA(A) receptor autoantibody test, DPPX autoantibody test, and IgLON5 autoantibody test.
Neurology- UpToDate, Wolters Kluwer contributing author, receive royalties Medlink Neurology contributing author, receive royalties
NONE
Advance Medical
NONE
NONE
NONE
Research support (allosteric modulation of NMDAR) from SAGE Therapeutics
-Instituto Carlos III/FEDER (FIS, 17/00234, CIBERER CB15/00010, Proyectos Integrados de Excelencia, PIE 16/00014 and AC18/00009). -Agencia de Gestio d'Ajuts Universitaris i de Recerca (AGAUR), and CERCA Programme Generalitat de Catalunya
NONE
Safra Foundation Sage therapeutics Cellex Foundation La Caixa Health Foundation
NONE
NONE
Ma2 autoantibody test (tech/invention), Athena Diagostics via Memoral Sloan Kettering, current NMDA receptor, GABA(B) receptor autoantibody tests (tech/invention), Euroimmun, Inc via University of Pennsylvania, current GABA(A) receptor, DPPX and IgLON5 autoantibody tests (tech/invention), Euroimmun, Inc via Institucio Catalana de Recerca i Estudis Avancats (ICREA); Institut d'Investigacions Biomediques August Pi i Sunyer (IDIBAPS), current
NONE
NONE
NONE
- From the Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) (A.G.-S., M.R., A.P., V.B., E.A., E.M., H.A., M.S., F.M., M.P., B.J., S.G., J.P., J.D.), Hospital Clínic, Universitat de Barcelona; Departament de Biomedicina (A.P., V.B., S.G.), Facultat de Medicina, Institut de Neurociències, Universitat de Barcelona; Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas (CIBERNED) (A.P., V.B., S.G.), Madrid; Medical Statistics Core Facility (J.R.), IDIBAPS and Hospital Clínic, Barcelona; Biostatistics Unit (J.R.), School of Medicine, Universitat Autònoma de Barcelona; Centro de Investigaciones Biomédicas en Red de Enfermedades Raras (CIBERER) (J.D.), Madrid, Spain; Department of Neurology (J.D.), University of Pennsylvania, Philadelphia; and Institució Catalana de Recerca i Estudis Avançats (ICREA) (J.D.), Barcelona, Spain.
- Correspondence
Dr. Dalmau jdalmau{at}clinic.cat
Article usage
Letters: Rapid online correspondence
REQUIREMENTS
You must ensure that your Disclosures have been updated within the previous six months. Please go to our Submission Site to add or update your Disclosure information.
Your co-authors must send a completed Publishing Agreement Form to Neurology Staff (not necessary for the lead/corresponding author as the form below will suffice) before you upload your comment.
If you are responding to a comment that was written about an article you originally authored:
You (and co-authors) do not need to fill out forms or check disclosures as author forms are still valid
and apply to letter.
Submission specifications:
- Submissions must be < 200 words with < 5 references. Reference 1 must be the article on which you are commenting.
- Submissions should not have more than 5 authors. (Exception: original author replies can include all original authors of the article)
- Submit only on articles published within 6 months of issue date.
- Do not be redundant. Read any comments already posted on the article prior to submission.
- Submitted comments are subject to editing and editor review prior to posting.
You May Also be Interested in
Hastening the Diagnosis of Amyotrophic Lateral Sclerosis
Dr. Brian Callaghan and Dr. Kellen Quigg
► Watch
Related Articles
- No related articles found.
Topics Discussed
Alert Me
Recommended articles
-
Special Article
NMDA receptor encephalitis and other antibody-mediated disorders of the synapseThe 2016 Cotzias LectureJosep Dalmau et al.Neurology, December 05, 2016 -
Article
Human neurexin-3α antibodies associate with encephalitis and alter synapse developmentNuria Gresa-Arribas, Jesús Planagumà, Mar Petit-Pedrol et al.Neurology, May 11, 2016 -
What's Happening
What's Happening in Neurology® Neuroimmunology & Neuroinflammationet al.Neurology, March 22, 2021 -
Article
NMDA receptor antibodiesA rare association in inflammatory demyelinating diseasesMelanie Ramberger, Gabriel Bsteh, Kathrin Schanda et al.Neurology - Neuroimmunology Neuroinflammation, August 13, 2015