Article Figures & Data
Figures
- Figure 1 Relationship Between Whole-Brain Volume Loss and Age and Disease Duration
Relationship between annualized whole-brain volume loss rate and age (A) and disease duration as continuous variables (B) with a smooth curve fitted by loess regression technique; relationship between mean annualized whole-brain volume loss rates at different ages (C) and disease duration intervals (D); and relationship between mean fitted individual slopes (regression coefficients) of annualized whole-brain volume loss rate trajectories at different ages (E) and disease duration intervals (F). The dotted black horizontal line represents no change in annualized whole-brain volume loss rate, and the red dotted horizontal line represents the reference cutoff value (0.4% per year) for pathologic whole-brain volume change.
- Figure 2 T2 Lesion Volume Changes in Different Age and Disease Duration Intervals
Mean annualized T2 lesion volume absolute changes in different age (A) and disease duration (B) intervals. Statistical analysis was performed on continuous data.
- Figure 3 Whole-Brain Volume Loss After Escalation of Treatment
Evolution of annualized whole-brain volume loss after escalation from the low-efficacy on high/moderate-efficacy disease-modifying treatments. The treatment change occurred at time 0.
Tables
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