B-Cell Activity Predicts Response to Glatiramer Acetate and Interferon in Relapsing-Remitting Multiple Sclerosis
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Article Information
- Received July 23, 2020
- Accepted in final form January 12, 2021
- First Published March 11, 2021.
Author Disclosures
- Sabine Tacke, MSc (sabine.tacke{at}fau.de),
- Stefan Braune, MD (sbraune{at}neurotransdata.com),
- Damiano M. Rovituso, PhD (damianorovituso{at}yahoo.de),
- Tjalf Ziemssen, MD (tjalf.ziemssen{at}uniklinikum-dresden.de),
- Paul V. Lehmann, MD (paul.lehmann{at}immunospot.com),
- Heidi Dikow, MSc (hdikow{at}neurotransdata.com),
- Arnfin Bergmann, MD (abergmann{at}neurotransdata.com) and
- Stefanie Kuerten, MD, PhD
- Sabine Tacke, MSc (sabine.tacke{at}fau.de),
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- Stefan Braune, MD (sbraune{at}neurotransdata.com),
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1) Biogen 2) NeuroTransData
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1) NeuroTransData
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- Damiano M. Rovituso, PhD (damianorovituso{at}yahoo.de),
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(1) Biorasi GmbH (CRO), CTA/CRA, >1 year (Apr 2019 - ongoing) (2) Uniklinik Würzburg, Postdoc, < 1 year (Dec 2017 - Jul 2018) (3) University of Würzburg, Postdoc, 1 year (Aug 2016 - Oct 2017) (employment related to this manuscript)
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- Tjalf Ziemssen, MD (tjalf.ziemssen{at}uniklinikum-dresden.de),
(1) Bayer Healthcare (2) Biogen Idec (3) Novartis (4) Merck Serono (5) Teva (6) Genzyme (7) Roche (8) Celgene; all commercial
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Speaker honorarium for all commercial entities (1) Bayer Healthcare (2) Biogen Idec (3) Sanofi Genzyme (4) Celgene (5) Roche (6) Novartis (7) Teva (8) Almirall (o) Merck
(1) BMC Neurology, Section editor, demyelinating disorders, since 2016
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(1) Biogen Idec (2) Sanofi Genzyme (3) Novartis (4) Teva
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- Paul V. Lehmann, MD (paul.lehmann{at}immunospot.com),
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I am co-inventor on an issued patent that uses B cell ELISPOT to diagnose Multiple Sclerosis
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I am the Founder and CEO of CTL, a company that focuses on ELISPOT-based immune diagnostic.
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- Heidi Dikow, MSc (hdikow{at}neurotransdata.com),
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NeuroTransData GmbH, Data Scientist, 3 years
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- Arnfin Bergmann, MD (abergmann{at}neurotransdata.com) and
(1) NeuroTransData GmbH
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(1) Novartis (2) Servier
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- Stefanie Kuerten, MD, PhD
(1) Novartis
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(1) Novartis (2) Sanofi Genzyme (3) Roche
(1) International Journal of Molecular Sciences, Associate Editor, 2020-now (2) International Journal of Molecular Sciences, Special Issue Guest Editor, 2020 (3) BMC Neurology, Associate Editor, 2013-now
(1) ELISPOT technology for the detection of autoimmune responses
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(1) NeuroTransData GmbH
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- From the Institute of Anatomy and Cell Biology (S.T., D.M.R., S.K.), Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Germany; NeuroTransData (S.B., H.D., A.B.), Neuburg an der Donau, Germany; Department of Neurology (T.Z.), Center of Clinical Neuroscience, University Hospital Carl Gustav Carus, Technische Universität Dresden, Germany; and Research and Development Department (P.V.L.), Cellular Technology Limited, Shaker Heights, OH.
- Correspondence
Dr. Kuerten stefanie.kuerten{at}uni-bonn.de
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