Inhibition of Maternal-to-Fetal Transfer of IgG Antibodies by FcRn Blockade in a Mouse Model of Arthrogryposis Multiplex Congenita
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Article Information
- Received January 24, 2021
- Accepted in final form March 17, 2021
- First Published May 27, 2021.
Author Disclosures
- Ester Coutinho, MD, DPhil (estercoutinho{at}gmail.com),
- Leslie Jacobson, DPhil (leslie.jacobson{at}ndcn.ox.ac.uk),
- Anthony Shock, PhD (tony.shock{at}ucb.com),
- Bryan Smith, PhD (bryan.smith{at}ucb.com),
- Anthony Vernon, PhD* (anthony.vernon{at}kcl.ac.uk) and
- Angela Vincent, MD, FRCPath*
- Ester Coutinho, MD, DPhil (estercoutinho{at}gmail.com),
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I am funded through a clinical fellowship from the MRC Centre for Neurodevelopmental disorders (Out of Programme Experience) since June 2019.
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- Leslie Jacobson, DPhil (leslie.jacobson{at}ndcn.ox.ac.uk),
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- Anthony Shock, PhD (tony.shock{at}ucb.com),
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(1) UCB Pharma as Research Director, and employed for the past 29 years
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- Bryan Smith, PhD (bryan.smith{at}ucb.com),
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Paid consultant for UCB, not directly related to this manuscript.
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Hold UCB stock option currentlyc.
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- Anthony Vernon, PhD* (anthony.vernon{at}kcl.ac.uk) and
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(1) UCB Biopharma SPRL
(1) NC3Rs National Centre for the Replacement, Refinement and Reduction of Animals in Research, NC/S001506/1, Principle Investigator, 2019-2022.
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- Angela Vincent, MD, FRCPath*
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Travel reimbursement from neurological associations for lectures at meetings.
Advisory Editorial Board Neurology 2014 - Advisory Editorial Board Annals of Neurology 2018 - Associate Editor for Brain ended 2013
Hold patents with Oxford University for MuSK antibodies and for LGI1/CASPR2 antibodies. Receive a proportion of royalties from these tests.
Royalties for Clinical Neuroimmunology (Blackwell Publishing, 2005) and Inflammatory and Autoimmune Disorders of the Nervous System in Children (Mac Keith Press 2010) and for Pittock and Vincent Handbook of Neurology 2017 (Elsevier).
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NIHR general support for antibody work finished 2016
FNRS honorarium for Prize Panel work £2000 2017 World Federation of Neurology prize £5000 2017 (donated back) Zuelch Prize E15000 from MPG 2018 (an award, unsolicited)
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- From the Department of Basic and Clinical Neuroscience (E.C., A. Vernon), Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Clinical Neuroscience Institute; Medical Research Council Centre for Neurodevelopmental Disorders (E.C., A. Vernon), King's College London; Nuffield Department of Clinical Neurosciences (L.J., A. Vincent), University of Oxford; and UCB Pharma (A.S., B.S.), Slough, United Kingdom.
- Correspondence
Dr. Vincent angela.vincent{at}ndcn.ox.ac.uk
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