Antiplexin D1 Antibodies Relate to Small Fiber Neuropathy and Induce Neuropathic Pain in Animals
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Article Information
- Received December 3, 2020
- Accepted in final form April 5, 2021
- First Published June 7, 2021.
Author Disclosures
- Takayuki Fujii, MD, PhD (takayuki{at}neuro.med.kyushu-u.ac.jp),
- Eun-Jae Lee, MD, PhD (siverash{at}gmail.com),
- Yukino Miyachi, MSc (ykno.m.223{at}gmail.com),
- Ryo Yamasaki, MD, PhD (ryoya{at}neuro.med.kyushu-u.ac.jp),
- Young-Min Lim, MD, PhD (limy{at}amc.seoul.kr),
- Kyoko Iinuma, MSc (kyoiinuma{at}gmail.com),
- Ayako Sakoda, MD, PhD (sakoda-a{at}neuro.med.kyushu-u.ac.jp),
- Kwang-Kuk Kim, MD, PhD (kkim601{at}gmail.com) and
- Jun-ichi Kira, MD, PhD
- Takayuki Fujii, MD, PhD (takayuki{at}neuro.med.kyushu-u.ac.jp),
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(1)Takeda Pharmaceutical Company, speaker honoraria (2)Eisai, speaker honoraria
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(1) Mitsubishi Tanabe Pharma, (2) Osoegawa Neurology Clinic, (3) Bayer Yakuhin, Ltd., (4) the Japan Blood Products Organization
(1) the Japan Society for the Promotion of Science (JSPS) KAKENHI, grant number JP19K17037, principal investigator, 2019-2020
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- Eun-Jae Lee, MD, PhD (siverash{at}gmail.com),
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Ministry of Science and ICT, South Korea (NRF- 2018R1C1B6008884, NRF-2018M3A9E8066249), Ministry of Health & Welfare, South Korea (HI18C2383)
Asan Institute for Life Science (2019-0830, 2019-0851), Asan Medical Center, Seoul, South Korea
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- Yukino Miyachi, MSc (ykno.m.223{at}gmail.com),
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- Ryo Yamasaki, MD, PhD (ryoya{at}neuro.med.kyushu-u.ac.jp),
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Clinical and experimental neuroimmunology, managing editor, since 2016 until now
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- Young-Min Lim, MD, PhD (limy{at}amc.seoul.kr),
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- Kyoko Iinuma, MSc (kyoiinuma{at}gmail.com),
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- Ayako Sakoda, MD, PhD (sakoda-a{at}neuro.med.kyushu-u.ac.jp),
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- Kwang-Kuk Kim, MD, PhD (kkim601{at}gmail.com) and
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- Jun-ichi Kira, MD, PhD
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JK received speaking fees and/or honoraria from (1) Novartis Pharma, (2) Mitsubishi Tanabe Pharma, (3) Boehringer Ingelheim, (4) Teijin Pharma, (5) the Takeda Pharmaceutical Company, (6) Otsuka Pharmaceutical, (7) Astellas Pharma, (8) Pfizer Japan, and (9) Eisai.
(1) Multiple Sclerosis Journal, Editorial Board Member, 2006-, (2) BMC Medicine, Editorial Board Member, 2010-, (3) Journal of the Neurological Sciences, Editorial Board Member, 2010-, (4) Multiple Sclerosis and Related Disorders, Editorial Board Member, Section Editor, 2011-, (5) PLOS ONE, Editorial Board Member, 2011-, (6) Frontiers in Immunology, Associate Editor, 2017-
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(1) Biogen Japan (consultancy, since 2009)
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(1) Novartis Pharma, (2) Boehringer Ingelheim, (3) Teijin Pharma, (4) Takeda Pharmaceutical Company, (5) Otsuka Pharmaceutical, (6) Astellas Pharma, (7) Pfizer Japan, (8) Eisai, (9) Dainippon-Sumitomo Pharmaceutical, (10) Tanabe-Mitsubishi Pharmaceutical, (11) Japan Blood Products Organization, (12) Bayer, (13) Yamasa corporation
(1) Grant-in-Aid for Scientific Research on Innovative Areas (MEXT KAKENHI), 25117012, Principal Investigator, 2013-2018, (2) Grant-in-Aid for Scientific Research on Innovative Areas (MEXT KAKENHI), 25117001, Co- investigator, 2013-2018, (3) Grant-in-Aid for Scientific Research on Innovative Areas (MEXT KAKENHI), 15K21729, Co-investigator, 2015-2018, (4) Grant-in-Aid for Challenging Exploratory Research (JSPS KAKENHI), 15K15341, Principal Investigator, 2015-2017, (5) Grant-in-Aid for Scientific Research (C) (JSPS KAKENHI), 15K09343, Co- investigator, 2015-2018, (6) Grant-in-Aid for Scientific Research (C) (JSPS KAKENHI), 16K10727, Co- investigator, 2016-2019, (7) Grant-in-Aid for Scientific Research (A) (JSPS KAKENHI), 16H02657, Principal Investigator, 2016-2019, (8) Grant-in-Aid for Challenging Exploratory Research (JSPS KAKENHI), 17K19663, Principal Investigator, 2017-2019, (9) Grant-in-Aid for Scientific Research (C) (JSPS KAKENHI), 18K07529, Co- investigator, 2018-2021, (10) Grant-in-Aid for Scientific Research (A) (JSPS KAKENHI), 19H01045, Principal Investigator, 2019-2022, (11) Practical Research Project for Rare/Intractable Diseases" from Japan Agency for Medical Research and Development, AMED, Japan, 16ek0109039h0003, Principal Investigator, 2016-2017, (12) Practical Research Project for Rare/Intractable Diseases" from Japan Agency for Medical Research and Development, AMED, Japan, 17ek0109115h0003, Principal Investigator, 2015-2018, (13) Practical Research Project for Rare/Intractable Diseases" from Japan Agency for Medical Research and Development, AMED, Japan, 18ek0109376h0001, Principal Investigator, 2018-2021, (14) Practical Research Project for Rare/Intractable Diseases" from Japan Agency for Medical Research and Development, AMED, Japan, 18ek0109308h0001, Principal Investigator, 2018-2021, (15) Health and Labour Sciences Research Grant on Intractable Diseases from the Ministry of Health, Labour, and Welfare, Japan, H29- Nanchitou(Nan)-Shitei-001, Co-investigator, 2017-2020, (16) Health and Labour Sciences Research Grant on Intractable Diseases from the Ministry of Health, Labour, and Welfare, Japan, H29-Nanchitou(Nan)-Ippan-043, Co- investigator, 2017-2020, (17) Health and Labour Sciences Research Grant on Intractable Diseases from the Ministry of Health, Labour, and Welfare, Japan, H29- Nanchitou(Nan)-Ippan-033, Co-investigator, 2017-2020, (18) Health and Labour Sciences Research Grant on Intractable Diseases from the Ministry of Health, Labour, and Welfare, Japan, H29-Nanchitou(Nan)-Ippan-009, Co- investigator, 2017-2020, (19) Health and Labour Sciences Research Grant on Intractable Diseases from the Ministry of Health, Labour, and Welfare, Japan, H28- Nanchitou(Nan)-Ippan-025, Principal Investigator, 2016- 2019, (20) Health and Labour Sciences Research Grant on Intractable Diseases from the Ministry of Health, Labour, and Welfare, Japan, H28-Nanchitou(Nan)-Ippan-018, Co-investigator, 2016-2019
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- From the Department of Neurology (T.F., Y.M., R.Y., K.I., A.S., J.-i.K.), Neurological Institute, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan; Department of Neurology (E.-J.L., Y.-M.L., K.-K.K.), Asan Medical Center, University of Ulsan, College of Medicine, Seoul, South Korea; Translational Neuroscience Center (J.-i.K.), Graduate School of Medicine, and School of Pharmacy at Fukuoka, International University of Health and Welfare, Okawa; and Department of Neurology (J.-i.K.), Brain and Nerve Center, Fukuoka Central Hospital, International University of Health and Welfare, Japan.
- Correspondence
Dr. Kira kira{at}neuro.med.kyushu-u.ac.jp
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