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Figures
- Figure 1 Optic Nerve MRI Findings in a Patient With CIS
(A) Patient with CIS presenting a left clinical episode of acute optic neuritis. A symptomatic optic nerve lesion (arrowhead) and a right asymptomatic optic nerve lesion (white arrow) were detected on 3D-Double-Inversion Recovery MR sequence. MRI reconstruction of left and right optic nerves showing symptomatic (arrowheads) and asymptomatic (white arrows) lesions in sagittal optic nerve planes (B) and coronal planes (C). CIS = clinically isolated syndrome
- Figure 2 Flowchart of IRMANO Cohort and the Corresponding Eyes' Subgroups According to the Occurrence of an Acute ON, ON History, and Optic Nerve MRI Data
The authors recruited 51 patients presenting an acute episode of ON. One patient with acute ON did not present any optic nerve lesion on MRI. One patient with RRMS presented a bilateral acute ON. All eyes with a history of ON presented an optic nerve lesion. Some patients with CIS and RRMS presented an asymptomatic optic nerve lesion on the fellow eye. CIS = clinically isolated syndrome; DIR = double-inversion recovery; NMOSD = neuromyelitis optica spectrum disorders; ON = optic neuritis; RRMS = relapsing-remitting multiple sclerosis.
- Figure 3 Optic Nerve MRI of a CIS Patient With Detection of a New Asymptomatic Optic Nerve Lesion During the Follow-up
Optic nerve MRI of a patient with CIS presenting a left acute optic neuritis. At inclusion, no lesion was detected on the right optic nerve. At M12, a new right asymptomatic retrobulbar optic nerve DIR hypersignal was detected (white arrows). CIS = clinically isolated syndrome.
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