Skip to main content
Advertisement
  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
    • Education
  • Online Sections
    • COVID-19
    • Inclusion, Diversity, Equity, Anti-racism, & Social Justice (IDEAS)
    • Innovations in Care Delivery
    • Practice Current
    • Residents & Fellows
    • Without Borders
    • Practice Buzz
  • Collections
    • Topics A-Z
    • Disputes & Debates
    • Health Disparities
    • Infographics
    • Null Hypothesis
    • Patient Pages
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center

Advanced Search

Main menu

  • Neurology.org
  • Journals
    • Neurology
    • Clinical Practice
    • Genetics
    • Neuroimmunology & Neuroinflammation
    • Education
  • Online Sections
    • COVID-19
    • Inclusion, Diversity, Equity, Anti-racism, & Social Justice (IDEAS)
    • Innovations in Care Delivery
    • Practice Current
    • Residents & Fellows
    • Without Borders
    • Practice Buzz
  • Collections
    • Topics A-Z
    • Disputes & Debates
    • Health Disparities
    • Infographics
    • Null Hypothesis
    • Patient Pages
    • Translations
  • Podcast
  • CME
  • About
    • About the Journals
    • Contact Us
    • Editorial Board
  • Authors
    • Submit a Manuscript
    • Author Center
  • Home
  • Articles
  • Issues
  • COVID-19 Article Hub

User menu

  • My Alerts
  • Log in

Search

  • Advanced search
Neurology Neuroimmunology & Neuroinflammation
Home
A peer-reviewed clinical and translational neurology open access journal
  • My Alerts
  • Log in
Site Logo
  • Home
  • Articles
  • Issues
  • COVID-19 Article Hub

Reader response: Clinical and MRI phenotypes of sarcoidosis-associated myelopathy

  • Otto Jesus Hernandez Fustes, Neurologist, Clinical Neurophysiology, CHC-UFPR
Submitted June 26, 2020

I read with great interest the article by Murphy et al.1 We think the article offers a good opportunity for resident physicians and specialists to review neurologic manifestations of sarcoidosis.

Sarcoidosis is an auto-inflammatory disorder characterized by the development of granulomatous inflammation in affected tissues. Case series comprising 19–54 cases showed that around half of patients have isolated cranial neuropathies—of which the facial nerve is by far the most common—with peripheral nerve involvement in 10% and muscle involvement in 5%, and with brain and spinal cord lesions accounting for the remainder—16%–70% of these series.2

Murphy and colleagues make an excellent presentation of the clinical and imaging characteristics (MRI) of the largest published series of patients. Most patients had sensory symptoms. As a suggestion, we would like the authors to have complemented the assessment with a neurophysiological study with the electroneuromyography and somatosensory evoked potential. Electrodiagnostic testing may be useful in patients with suspected myelopathy, neuropathy or myopathy.

We congratulate the authors for the report, and the opportunity to delve into a topic so interesting that it will serve as a motivation for further studies.

Disclosure

The author reports no relevant disclosures. Contact journal@neurology.org for full disclosures.

References

  1. Murphy OC, Salazar-Camelo A, Jimenez JA, et al. Clinical and MRI phenotypes of sarcoidosis-associated myelopathy. Neurol Neuroimmunol Neuroinflamm 2020;7:e722.
  2. Kidd DP. Neurosarcoidosis: clinical manifestations, investigation and treatment. Pract Neurol 2020;20:199–212.

Navigate back to article

Neurology - Neuroimmunology Neuroinflammation: 9 (4)

Articles

  • Articles
  • Issues
  • Popular Articles

About

  • About the Journals
  • Ethics Policies
  • Editors & Editorial Board
  • Contact Us
  • Advertise

Submit

  • Author Center
  • Submit a Manuscript
  • Information for Reviewers
  • AAN Guidelines
  • Permissions

Subscribers

  • Subscribe
  • Sign up for eAlerts
  • RSS Feed
Site Logo
  • Visit neurology Template on Facebook
  • Follow neurology Template on Twitter
  • Visit Neurology on YouTube
  • Neurology
  • Neurology: Clinical Practice
  • Neurology: Genetics
  • Neurology: Neuroimmunology & Neuroinflammation
  • Neurology: Education
  • AAN.com
  • AANnews
  • Continuum
  • Brain & Life
  • Neurology Today

Wolters Kluwer Logo

Neurology: Neuroimmunology & Neuroinflammation
Online ISSN: 2332-7812

© 2022 American Academy of Neurology

  • Privacy Policy
  • Feedback
  • Advertise