Is there any role of serum Parathyroid hormone as a risk factors for recurrent transeverse myelitis
Rameshwar N.Chaurasia, Associate Professor Neurology, Department of Neurology, Institute of Medical Sciences, Banaras Hindu University, varanasi-221005goforrameshwar@gmail.com
Submitted June 25, 2014
I read with interest the Kimbrough et al. article on the predictors of transverse myelitis recurrence. [1] No double blind study has yet proven low vitamin D levels as a causative factor or risk factor for recurrent transverse myelitis or multiple sclerosis. Kimbrough et al., along with another study, have shown the association between low vitamin D levels and recurrent transverse myelitis, neither mentioning whether serum parathyroid hormone level was also abnormal or not. [1, 2] Even today, in the era of neuroimaging, evoked potentials play a major role in early prediction and diagnosis of multiple sclerosis, NMO, and NMOSD. Particularly in countries like Asia and Africa, where rickets is found more in children, a large study needs to confirm or solidify results of studies showing a low vitamin D level risk factor and the role of serum parathyroid in such diseases as a causative factor.
1. Dorlan J. Kimbrough et al. Predictors of recurrence following an initial episode of transverse myelitis. Neurol Neuroimmunol Neuroinflammation 2014;1(1): e4.
2. MA Mealy et al. Low serum vitamin D levels and recurrent inflammatory spinal cord disease. Arch Neurol 2012;69:352-356
1. Dorlan J. Kimbrough et al. Predictors of recurrence following an initial episode of transverse myelitis. Neurol Neuroimmunol Neuroinflammation 2014;1(1): e4.
2. MA Mealy et al. Low serum vitamin D levels and recurrent inflammatory spinal cord disease. Arch Neurol 2012;69:352-356